Free form shapes are often used to fulfil both aesthetic and design constraints applied to parametric models currently adopted in CAD environments. Up to now, designers and engine...
Vincent Cheutet, Jean-Philippe Pernot, Jean-Claude...
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
Daniel Rios, William M. McLaren, Yuan Chen, Ewan B...
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
The practical realization of managing and executing large scale scientific computations efficiently and reliably is quite challenging. Scientific computations often invo...
Yong Zhao, Ioan Raicu, Ian T. Foster, Mihael Hateg...