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» Margin based feature selection - theory and algorithms
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BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2010
160views more  BMCBI 2010»
13 years 7 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BMCBI
2008
173views more  BMCBI 2008»
13 years 7 months ago
Improved machine learning method for analysis of gas phase chemistry of peptides
Background: Accurate peptide identification is important to high-throughput proteomics analyses that use mass spectrometry. Search programs compare fragmentation spectra (MS/MS) o...
Allison Gehrke, Shaojun Sun, Lukasz A. Kurgan, Nat...
BMCBI
2005
124views more  BMCBI 2005»
13 years 7 months ago
ErmineJ: Tool for functional analysis of gene expression data sets
Background: It is common for the results of a microarray study to be analyzed in the context of biologically-motivated groups of genes such as pathways or Gene Ontology categories...
Homin K. Lee, William Braynen, Kiran Keshav, Paul ...
SSDBM
2010
IEEE
133views Database» more  SSDBM 2010»
13 years 5 months ago
PrefIndex: An Efficient Supergraph Containment Search Technique
Graphs are prevailingly used in many applications to model complex data structures. In this paper, we study the problem of supergraph containment search. To avoid the NP-complete s...
Gaoping Zhu, Xuemin Lin, Wenjie Zhang, Wei Wang, H...