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BMCBI
2008
148views more  BMCBI 2008»
13 years 11 months ago
Discovering biclusters in gene expression data based on high-dimensional linear geometries
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Xiangchao Gan, Alan Wee-Chung Liew, Hong Yan
BMCBI
2008
117views more  BMCBI 2008»
13 years 11 months ago
An iterative block-shifting approach to retention time alignment that preserves the shape and area of gas chromatography-mass sp
Background: Metabolomics, petroleum and biodiesel chemistry, biomarker discovery, and other fields which rely on high-resolution profiling of complex chemical mixtures generate da...
Minho Chae, Robert J. Shmookler Reis, John J. Thad...
BMCBI
2008
147views more  BMCBI 2008»
13 years 11 months ago
Assessment of disease named entity recognition on a corpus of annotated sentences
Background: In recent years, the recognition of semantic types from the biomedical scientific literature has been focused on named entities like protein and gene names (PGNs) and ...
Antonio Jimeno-Yepes, Ernesto Jiménez-Ruiz,...
BMCBI
2006
88views more  BMCBI 2006»
13 years 11 months ago
Protein kinases associated with the yeast phosphoproteome
Background: Protein phosphorylation is an extremely important mechanism of cellular regulation. A large-scale study of phosphoproteins in a whole-cell lysate of Saccharomyces cere...
Ross I. Brinkworth, Alan L. Munn, Bostjan Kobe
BMCBI
2006
172views more  BMCBI 2006»
13 years 11 months ago
A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
Zhuo Zhang, Shiwei Sun, Xiaopeng Zhu, Suhua Chang,...