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TCBB
2008
122views more  TCBB 2008»
13 years 10 months ago
Mixed Integer Linear Programming for Maximum-Parsimony Phylogeny Inference
Reconstruction of phylogenetic trees is a fundamental problem in computational biology. While excellent heuristic methods are available for many variants of this problem, new adva...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...
ICML
2003
IEEE
14 years 11 months ago
Learning Mixture Models with the Latent Maximum Entropy Principle
We present a new approach to estimating mixture models based on a new inference principle we have proposed: the latent maximum entropy principle (LME). LME is different both from ...
Shaojun Wang, Dale Schuurmans, Fuchun Peng, Yunxin...
ICML
2009
IEEE
14 years 11 months ago
MedLDA: maximum margin supervised topic models for regression and classification
Supervised topic models utilize document's side information for discovering predictive low dimensional representations of documents; and existing models apply likelihoodbased...
Jun Zhu, Amr Ahmed, Eric P. Xing
BMCBI
2006
116views more  BMCBI 2006»
13 years 11 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...