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» Maximum entropy methods for biological sequence modeling
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RECOMB
2003
Springer
14 years 9 months ago
A multi-expert system for the automatic detection of protein domains from sequence information
We describe a novel method for detecting the domain structure of a protein from sequence information alone. The method is based on analyzing multiple sequence alignments that are ...
Niranjan Nagarajan, Golan Yona
ICDM
2006
IEEE
122views Data Mining» more  ICDM 2006»
14 years 3 months ago
Optimal Segmentation Using Tree Models
Sequence data are abundant in application areas such as computational biology, environmental sciences, and telecommunications. Many real-life sequences have a strong segmental str...
Robert Gwadera, Aristides Gionis, Heikki Mannila
CSDA
2007
116views more  CSDA 2007»
13 years 9 months ago
Exploring the state sequence space for hidden Markov and semi-Markov chains
The knowledge of the state sequences that explain a given observed sequence for a known hidden Markovian model is the basis of various methods that may be divided into three categ...
Yann Guédon
BMCBI
2006
143views more  BMCBI 2006»
13 years 9 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
JCB
2000
103views more  JCB 2000»
13 years 9 months ago
Testing for Differentially-Expressed Genes by Maximum-Likelihood Analysis of Microarray Data
Although two-color uorescent DNA microarrays are now standard equipment in many molecular biology laboratories, methods for identifying differentially expressed genes in microarra...
Trey Ideker, Vesteinn Thorsson, Andrew F. Siegel, ...