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» Maximum entropy methods for biological sequence modeling
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RECOMB
2003
Springer
14 years 9 months ago
Haplotype reconstruction from SNP alignment
In this paper, we describe a method for statistical reconstruction of haplotypes from a set of aligned SNP fragments. We consider the case of a pair of homologous human chromosome...
Lei Li, Jong Hyun Kim, Michael S. Waterman
BMCBI
2006
165views more  BMCBI 2006»
13 years 9 months ago
Improving the quality of protein structure models by selecting from alignment alternatives
Background: In the area of protein structure prediction, recently a lot of effort has gone into the development of Model Quality Assessment Programs (MQAPs). MQAPs distinguish hig...
Ingolf Sommer, Stefano Toppo, Oliver Sander, Thoma...
IPPS
2006
IEEE
14 years 3 months ago
Phylogenetic models of rate heterogeneity: a high performance computing perspective
Inference of phylogenetic trees using the maximum likelihood (ML) method is NP-hard. Furthermore, the computation of the likelihood function for huge trees of more than 1,000 orga...
Alexandros Stamatakis
ICASSP
2007
IEEE
14 years 3 months ago
Toward Turbo Decoding of RNA Secondary Structure
We propose an iterative probabilistic algorithm for estimation of RNA secondary structure using sequence data from two homologous sequences. The method is intended to exploit inte...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
ICASSP
2011
IEEE
13 years 26 days ago
Joint modeling of observed inter-arrival times and waveform data with multiple hidden states for neural spike-sorting
We present a novel, maximum likelihood framework for automatic spike-sorting based on a joint statistical model of action potential waveform shape and inter-spike interval duratio...
Brett Matthews, Mark Clements