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BMCBI
2010
109views more  BMCBI 2010»
13 years 10 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
BIOSYSTEMS
2008
77views more  BIOSYSTEMS 2008»
13 years 10 months ago
A computational model of chemotaxis-based cell aggregation
We present a computational model that successfully captures the cell behaviors that play important roles in 2-D cell aggregation. A virtual cell in our model is designed as an ind...
Manolya Eyiyurekli, Prakash Manley, Peter I. Lelke...
BMCBI
2010
176views more  BMCBI 2010»
13 years 10 months ago
Reverse engineering gene regulatory network from microarray data using linear time-variant model
nd: Gene regulatory network is an abstract mapping of gene regulations in living cells that can help to predict the system behavior of living organisms. Such prediction capability...
Mitra Kabir, Nasimul Noman, Hitoshi Iba
BMCBI
2010
147views more  BMCBI 2010»
13 years 10 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...
BMCBI
2010
74views more  BMCBI 2010»
13 years 10 months ago
A weighted q-gram method for glycan structure classification
Background: Glycobiology pertains to the study of carbohydrate sugar chains, or glycans, in a particular cell or organism. Many computational approaches have been proposed for ana...
Limin Li, Wai-Ki Ching, Takako Yamaguchi, Kiyoko F...