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BMCBI
2008
106views more  BMCBI 2008»
13 years 7 months ago
Identification of hot-spot residues in protein-protein interactions by computational docking
Background: The study of protein-protein interactions is becoming increasingly important for biotechnological and therapeutic reasons. We can define two major areas therein: the s...
Solène Grosdidier, Juan Fernández-Re...
BMCBI
2005
121views more  BMCBI 2005»
13 years 7 months ago
Automated methods of predicting the function of biological sequences using GO and BLAST
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
Craig E. Jones, Ute Baumann, Alfred L. Brown
JIB
2007
153views more  JIB 2007»
13 years 7 months ago
Duplicate detection of 2D-NMR Spectra
2D-Nuclear magnetic resonance (NMR) spectra are used in the (structural) analysis of small molecules. In contrast to 1D-NMR spectra, 2D-NMR spectra correlate the chemical shifts o...
Alexander Hinneburg, Björn Egert, Andrea Porz...
CGO
2010
IEEE
14 years 15 days ago
Taming hardware event samples for FDO compilation
Feedback-directed optimization (FDO) is effective in improving application runtime performance, but has not been widely adopted due to the tedious dual-compilation model, the difï...
Dehao Chen, Neil Vachharajani, Robert Hundt, Shih-...
CSDA
2006
169views more  CSDA 2006»
13 years 7 months ago
Generalized structured additive regression based on Bayesian P-splines
Generalized additive models (GAM) for modelling nonlinear effects of continuous covariates are now well established tools for the applied statistician. In this paper we develop Ba...
Andreas Brezger, Stefan Lang