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» Measuring complexity by measuring structure and organization
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FCT
2009
Springer
16 years 20 days ago
Directed Graphs of Entanglement Two
Entanglement is a complexity measure for directed graphs that was used to show that the variable hierarchy of the propositional modal µ-calculus is strict. While graphs of entangl...
Erich Grädel, Lukasz Kaiser, Roman Rabinovich
ICSM
1998
IEEE
15 years 10 months ago
Detection of Logical Coupling Based on Product Release History
Code-based metrics such as coupling and cohesion are used to measure a system's structural complexity. But dealing with large systems--those consisting of several millions of...
Harald Gall, Karin Hajek, Mehdi Jazayeri
BMCBI
2008
145views more  BMCBI 2008»
15 years 6 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
16 years 27 days ago
Application of Kernel Functions for Accurate Similarity Search in Large Chemical Databases
Background: Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screeni...
Xiaohong Wang, Jun Huan, Aaron M. Smalter, Gerald ...
BMCBI
2010
97views more  BMCBI 2010»
15 years 1 months ago
A semi-parametric Bayesian model for unsupervised differential co-expression analysis
Background: Differential co-expression analysis is an emerging strategy for characterizing disease related dysregulation of gene expression regulatory networks. Given pre-defined ...
Johannes M. Freudenberg, Siva Sivaganesan, Michael...