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» Meta-analysis of gene expression data: a predictor-based app...
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BMCBI
2004
150views more  BMCBI 2004»
13 years 10 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...
BMCBI
2005
102views more  BMCBI 2005»
13 years 10 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
BMCBI
2011
13 years 5 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
BMCBI
2010
105views more  BMCBI 2010»
13 years 11 months ago
Effects of scanning sensitivity and multiple scan algorithms on microarray data quality
Background: Maximizing the utility of DNA microarray data requires optimization of data acquisition through selection of an appropriate scanner setting. To increase the amount of ...
Andrew Williams, Errol M. Thomson
AIPS
2003
14 years 5 days ago
A Multi-Agent System-driven AI Planning Approach to Biological Pathway Discovery
As genomic and proteomic data is collected from highthroughput methods on a daily basis, subcellular components are identified and their in vitro behavior is characterized. Howev...
Salim Khan, William Gillis, Carl Schmidt, Keith De...