— Computational prediction of transcription factor’s binding sites and regulatory target genes has great value to the biological studies of cellular process. Existing practices...
Background: Our current understanding of transcription factor binding sites (TFBSs) in sequenced prokaryotic genomes is very limited due to the lack of an accurate and efficient c...
Shaoqiang Zhang, Shan Li, Phuc T. Pham, Zhengchang...
In this study, we seek to develop a predictive model for finding the strength of binding between a particular transcription factor (TF) variant and a particular DNA target variant...
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...