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» Methods for Predicting Target Sites of Transcription Factors
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BMCBI
2006
100views more  BMCBI 2006»
13 years 7 months ago
STAR: predicting recombination sites from amino acid sequence
Background: Designing novel proteins with site-directed recombination has enormous prospects. By locating effective recombination sites for swapping sequence parts, the probabilit...
Denis C. Bauer, Mikael Bodén, Ricarda Thier...
JBCB
2007
161views more  JBCB 2007»
13 years 7 months ago
On Cooperative Quasi-Equilibrium Models of transcriptional Regulation
Mechanistic models for transcriptional regulation are derived using the methods of equilibrium statistical mechanics, to model equilibrating processes that occur at a fast time sc...
Eric Mjolsness
TCS
2008
13 years 7 months ago
Detection of subtle variations as consensus motifs
We address the problem of detecting consensus motifs, that occur with subtle variations, across multiple sequences. These are usually functional domains in DNA sequences such as t...
Matteo Comin, Laxmi Parida
BIRD
2008
Springer
13 years 9 months ago
Translational Control by RNA-RNA Interaction: Improved Computation of RNA-RNA Binding Thermodynamics
The thermodynamics of RNA-RNA interaction consists of two components: the energy necessary to make a potential binding region accessible, i.e., unpaired, and the energy gained from...
Ulrike Mückstein, Hakim Tafer, Stephan H. F. ...
BMCBI
2010
177views more  BMCBI 2010»
13 years 7 months ago
Modular composition predicts kinase/substrate interactions
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Yichuan Liu, Aydin Tozeren