Living cells are the product of gene expression programs that involve the regulated transcription of thousands of genes. The elucidation of transcriptional regulatory networks in ...
Background: Subtle alternative splicing events involving tandem splice sites separated by a short (2-12 nucleotides) distance are frequent and evolutionarily widespread in eukaryo...
Identification of Transcription Factor Binding Site (TFBS) motifs in multiple DNA upstream sequences is important in understanding the mechanism of gene regulation. This identific...
Background: In expressed sequence tag (EST) sequencing, we are often interested in how many genes we can capture in an EST sample of a targeted size. This information provides ins...
Ji-Ping Z. Wang, Bruce G. Lindsay 0002, Liying Cui...
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...