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» Methods for Predicting Target Sites of Transcription Factors
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ECCB
2008
IEEE
14 years 1 months ago
SIRENE: supervised inference of regulatory networks
Living cells are the product of gene expression programs that involve the regulated transcription of thousands of genes. The elucidation of transcriptional regulatory networks in ...
Fantine Mordelet, Jean-Philippe Vert
BMCBI
2010
137views more  BMCBI 2010»
13 years 7 months ago
TassDB2 - A comprehensive database of subtle alternative splicing events
Background: Subtle alternative splicing events involving tandem splice sites separated by a short (2-12 nucleotides) distance are frequent and evolutionarily widespread in eukaryo...
Rileen Sinha, Thorsten Lenser, Niels Jahn, Ulrike ...
GECCO
2007
Springer
258views Optimization» more  GECCO 2007»
13 years 11 months ago
TFBS identification by position- and consensus-led genetic algorithm with local filtering
Identification of Transcription Factor Binding Site (TFBS) motifs in multiple DNA upstream sequences is important in understanding the mechanism of gene regulation. This identific...
Tak-Ming Chan, Kwong-Sak Leung, Kin-Hong Lee
BMCBI
2005
143views more  BMCBI 2005»
13 years 7 months ago
Gene capture prediction and overlap estimation in EST sequencing from one or multiple libraries
Background: In expressed sequence tag (EST) sequencing, we are often interested in how many genes we can capture in an EST sample of a targeted size. This information provides ins...
Ji-Ping Z. Wang, Bruce G. Lindsay 0002, Liying Cui...
BMCBI
2011
13 years 2 months ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein