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» Methods for Predicting Target Sites of Transcription Factors
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ALMOB
2006
155views more  ALMOB 2006»
13 years 7 months ago
Refining motifs by improving information content scores using neighborhood profile search
The main goal of the motif finding problem is to detect novel, over-represented unknown signals in a set of sequences (e.g. transcription factor binding sites in a genome). The mo...
Chandan K. Reddy, Yao-Chung Weng, Hsiao-Dong Chian...
BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
ALMOB
2008
95views more  ALMOB 2008»
13 years 7 months ago
A stitch in time: Efficient computation of genomic DNA melting bubbles
Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
Eivind Tøstesen
INFOCOM
2006
IEEE
14 years 1 months ago
Sleeping Coordination for Comprehensive Sensing Using Isotonic Regression and Domatic Partitions
— We address the problem of energy efficient sensing by adaptively coordinating the sleep schedules of sensor nodes while guaranteeing that values of sleeping nodes can be recov...
Farinaz Koushanfar, Nina Taft, Miodrag Potkonjak
BMCBI
2010
86views more  BMCBI 2010»
13 years 7 months ago
Fast motif recognition via application of statistical thresholds
Background: Improving the accuracy and efficiency of motif recognition is an important computational challenge that has application to detecting transcription factor binding sites...
Christina Boucher, James King