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BMCBI
2010
193views more  BMCBI 2010»
13 years 2 months ago
Mayday - integrative analytics for expression data
Background: DNA Microarrays have become the standard method for large scale analyses of gene expression and epigenomics. The increasing complexity and inherent noisiness of the ge...
Florian Battke, Stephan Symons, Kay Nieselt
BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
Evaluation of fecal mRNA reproducibility via a marginal transformed mixture modeling approach
Background: Developing and evaluating new technology that enables researchers to recover gene-expression levels of colonic cells from fecal samples could be key to a non-invasive ...
Nysia I. George, Joanne R. Lupton, Nancy D. Turner...
BMCBI
2008
129views more  BMCBI 2008»
13 years 7 months ago
Gene set enrichment analysis for non-monotone association and multiple experimental categories
Background: Recently, microarray data analyses using functional pathway information, e.g., gene set enrichment analysis (GSEA) and significance analysis of function and expression...
Rongheng Lin, Shuangshuang Dai, Richard D. Irwin, ...
BMCBI
2010
160views more  BMCBI 2010»
13 years 7 months ago
Annotation of gene promoters by integrative data-mining of ChIP-seq Pol-II enrichment data
Background: Use of alternative gene promoters that drive widespread cell-type, tissue-type or developmental gene regulation in mammalian genomes is a common phenomenon. Chromatin ...
Ravi Gupta, Priyankara Wikramasinghe, Anirban Bhat...
BMCBI
2011
13 years 2 months ago
Sequential Interim Analyses of Survival Data in DNA Microarray Experiments
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Andreas Leha, Tim Beißbarth, Klaus Jung