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BMCBI
2005
104views more  BMCBI 2005»
13 years 11 months ago
Scoring functions for transcription factor binding site prediction
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
Markus T. Friberg, Peter von Rohr, Gaston H. Gonne...
BMCBI
2005
97views more  BMCBI 2005»
13 years 11 months ago
Sequence variation in ligand binding sites in proteins
Background: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of the...
Thomas J. Magliery, Lynne Regan
BMCBI
2005
94views more  BMCBI 2005»
13 years 11 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya
BMCBI
2005
97views more  BMCBI 2005»
13 years 11 months ago
Comparative mapping of sequence-based and structure-based protein domains
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...
Ya Zhang, John-Marc Chandonia, Chris H. Q. Ding, S...
BMCBI
2005
102views more  BMCBI 2005»
13 years 11 months ago
BioCreAtIvE Task1A: entity identification with a stochastic tagger
Background: Our approach to Task 1A was inspired by Tanabe and Wilbur's ABGene system [1,2]. Like Tanabe and Wilbur, we approached the problem as one of part-of-speech taggin...
Shuhei Kinoshita, K. Bretonnel Cohen, Philip V. Og...
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