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    BMCBI
    2004
    151views more  BMCBI 2004»
    A computational approach for ordering signal transduction pathway components from genomics and proteomics Data
    13 years 10 months ago
    A computational approach for ordering signal transduction pathway components from genomics and proteomics Data
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    Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...
    Yin Liu, Hongyu Zhao
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    BMCBI
    2004
    158views more  BMCBI 2004»
    Incremental genetic K-means algorithm and its application in gene expression data analysis
    13 years 10 months ago
    Incremental genetic K-means algorithm and its application in gene expression data analysis
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    Background: In recent years, clustering algorithms have been effectively applied in molecular biology for gene expression data analysis. With the help of clustering algorithms suc...
    Yi Lu, Shiyong Lu, Farshad Fotouhi, Youping Deng, ...
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    BMCBI
    2004
    120views more  BMCBI 2004»
    pdb-care (PDB CArbohydrate REsidue check): a program to support annotation of complex carbohydrate structures in PDB files
    13 years 10 months ago
    pdb-care (PDB CArbohydrate REsidue check): a program to support annotation of complex carbohydrate structures in PDB files
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    Background: Carbohydrates are involved in a variety of fundamental biological processes and pathological situations. They therefore have a large pharmaceutical and diagnostic pote...
    Thomas Lütteke, Claus-Wilhelm von der Lieth
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    BMCBI
    2004
    177views more  BMCBI 2004»
    Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
    13 years 10 months ago
    Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
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    Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
    Andrew F. Neuwald, Jun S. Liu
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    BMCBI
    2004
    139views more  BMCBI 2004»
    Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
    13 years 10 months ago
    Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
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    Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
    Jeffrey P. Townsend
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