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» Methods to Create and Use Cross-Domain Analysis Patterns
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BMCBI
2010
144views more  BMCBI 2010»
13 years 8 months ago
Identifying overrepresented concepts in gene lists from literature: a statistical approach based on Poisson mixture model
Background: Large-scale genomic studies often identify large gene lists, for example, the genes sharing the same expression patterns. The interpretation of these gene lists is gen...
Xin He, Moushumi Sen Sarma, Xu Ling, Brant W. Chee...
ICIP
2003
IEEE
14 years 9 months ago
Morphological hat-transform scale spaces and their use in texture classification
In this paper we present a multi-scale morphological method for use in texture classification. A connected operator similar to the morphological hat-transform is defined, and two ...
Andrei Jalba, Jos B. T. M. Roerdink, Michael H. F....
CSB
2003
IEEE
14 years 1 months ago
Haplotype Motifs: An Algorithmic Approach to Locating Evolutionarily Conserved Patterns in Haploid Sequences
The promise of plentiful data on common human genetic variations has given hope that we will be able to uncover genetic factors behind common diseases that have proven difficult ...
Russell Schwartz
BMCBI
2004
208views more  BMCBI 2004»
13 years 8 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
PR
2007
112views more  PR 2007»
13 years 7 months ago
The effect of imbalanced data sets on LDA: A theoretical and empirical analysis
This paper demonstrates that the imbalanced data sets have a negative effect on the performance of LDA theoretically. This theoretical analysis is confirmed by the experimental r...
Jigang Xie, ZhengDing Qiu