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ALMOB
2008
127views more  ALMOB 2008»
13 years 7 months ago
HuMiTar: A sequence-based method for prediction of human microRNA targets
Background: MicroRNAs (miRs) are small noncoding RNAs that bind to complementary/partially complementary sites in the 3' untranslated regions of target genes to regulate prot...
Jishou Ruan, Hanzhe Chen, Lukasz A. Kurgan, Ke Che...
ISBRA
2010
Springer
13 years 6 months ago
A Consensus Tree Approach for Reconstructing Human Evolutionary History and Detecting Population Substructure
The random accumulation of variations in the human genome over time implicitly encodes a history of how human populations have arisen, dispersed, and intermixed since we emerged as...
Ming-Chi Tsai, Guy E. Blelloch, R. Ravi, Russell S...
ALGORITHMICA
2006
163views more  ALGORITHMICA 2006»
13 years 7 months ago
Building Large Phylogenetic Trees on Coarse-Grained Parallel Machines
Phylogenetic analysis is an area of computational biology concerned with the reconstruction of evolutionary relationships between organisms, genes, and gene families. Maximum likel...
Thomas M. Keane, Andrew J. Page, Thomas J. Naughto...
JCB
1998
92views more  JCB 1998»
13 years 7 months ago
Homology Detection via Family Pairwise Search
The function of an unknown biological sequence can often be accurately inferred by identifying sequences homologous to the original sequence. Given a query set of known homologs, ...
William Noble Grundy
BMCBI
2010
155views more  BMCBI 2010»
13 years 4 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...