Clustering or bi-clustering techniques have been proved quite useful in many application domains. A weakness of these techniques remains the poor support for grouping characterizat...
In this paper we present an evolutionary approach for inferring the structure and dynamics in gene circuits from observed expression kinetics. For representing the regulatory inte...
Novel, high-throughput technologies are challenging the core of algorithmic methods available in Computer Science. Microarray technologies give Life Sciences researchers the oppor...
To relax the homogeneity assumption of classical dynamic Bayesian networks (DBNs), various recent studies have combined DBNs with multiple changepoint processes. The underlying as...
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...