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» Mining Metabolic Networks for Optimal Drug Targets
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CMSB
2009
Springer
14 years 17 days ago
On Coupling Models Using Model-Checking: Effects of Irinotecan Injections on the Mammalian Cell Cycle
Abstract. In systems biology, the number of models of cellular processes increases rapidly, but re-using models in different contexts or for different questions remains a challengi...
Elisabetta De Maria, François Fages, Sylvai...
SASO
2008
IEEE
14 years 3 months ago
Cells Are Plausible Targets for High-Level Spatial Languages
—High level languages greatly increase the power of a programmer at the cost of programs that consume more s than those written at a lower level of abstraction. This inefficienc...
Jacob Beal, Jonathan Bachrach
CIBCB
2007
IEEE
13 years 10 months ago
Optimization of Bacterial Strains with Variable-Sized Evolutionary Algorithms
—In metabolic engineering it is difficult to identify which set of genetic manipulations will result in a microbial strain that achieves a desired production goal, due to the co...
Miguel Rocha, José P. Pinto, Isabel Rocha, ...
JIB
2007
119views more  JIB 2007»
13 years 8 months ago
VINEdb: a data warehouse for integration and interactive exploration of life science data
Control of cell proliferation, differentiation, activation and cell removal is crucial for the development and existence of multi-cellular organisms. Apoptosis, or programmed cell...
Sridhar Hariharaputran, Thoralf Töpel, Bj&oum...
IJCNN
2006
IEEE
14 years 2 months ago
Reconstruction of Gene Regulatory Networks from Temporal Microarray Data Using Pattern Recognition Techniques
- Gene regulatory networks allow us to study and understand genes’ roles in biological processes. Among others, regulatory networks help to identify pathway initiator genes and t...
Azhar Salim, Faramarz Valafar