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» Mining Metabolic Networks for Optimal Drug Targets
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CIKM
2010
Springer
13 years 3 months ago
Mining networks with shared items
Recent advances in data processing have enabled the generation of large and complex graphs. Many researchers have developed techniques to investigate informative structures within...
Jun Sese, Mio Seki, Mutsumi Fukuzaki
BMCBI
2004
93views more  BMCBI 2004»
13 years 8 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
BMCBI
2006
119views more  BMCBI 2006»
13 years 8 months ago
A methodology for the structural and functional analysis of signaling and regulatory networks
Background: Structural analysis of cellular interaction networks contributes to a deeper understanding of network-wide interdependencies, causal relationships, and basic functiona...
Steffen Klamt, Julio Saez-Rodriguez, Jonathan A. L...
BMCBI
2010
177views more  BMCBI 2010»
13 years 8 months ago
Modular composition predicts kinase/substrate interactions
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Yichuan Liu, Aydin Tozeren
KDD
2006
ACM
191views Data Mining» more  KDD 2006»
14 years 9 months ago
Beyond classification and ranking: constrained optimization of the ROI
Classification has been commonly used in many data mining projects in the financial service industry. For instance, to predict collectability of accounts receivable, a binary clas...
Lian Yan, Patrick Baldasare