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BMCBI
2010
160views more  BMCBI 2010»
13 years 7 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
Partial mixture model for tight clustering of gene expression time-course
Background: Tight clustering arose recently from a desire to obtain tighter and potentially more informative clusters in gene expression studies. Scattered genes with relatively l...
Yinyin Yuan, Chang-Tsun Li, Roland Wilson
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Biologically relevant effects of mRNA amplification on gene expression profiles
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
Rachel I. M. van Haaften, Blanche Schroen, Ben J. ...
BMCBI
2006
142views more  BMCBI 2006»
13 years 7 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins
BMCBI
2010
193views more  BMCBI 2010»
13 years 7 months ago
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
Jakub Mieczkowski, Magdalena E. Tyburczy, Michal D...