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» Mining phenotypes for gene function prediction
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RECOMB
2010
Springer
13 years 9 months ago
Subnetwork State Functions Define Dysregulated Subnetworks in Cancer
Abstract. Emerging research demonstrates the potential of proteinprotein interaction (PPI) networks in uncovering the mechanistic bases of cancers, through identification of intera...
Salim A. Chowdhury, Rod K. Nibbe, Mark R. Chance, ...
BMCBI
2006
98views more  BMCBI 2006»
13 years 7 months ago
The Secrets of a Functional Synapse - From a Computational and Experimental Viewpoint
Background: Neuronal communication is tightly regulated in time and in space. The neuronal transmission takes place in the nerve terminal, at a specialized structure called the sy...
Michal Linial
BMCBI
2004
229views more  BMCBI 2004»
13 years 7 months ago
Automatic annotation of protein motif function with Gene Ontology terms
Background: Conserved protein sequence motifs are short stretches of amino acid sequence patterns that potentially encode the function of proteins. Several sequence pattern search...
Xinghua Lu, Chengxiang Zhai, Vanathi Gopalakrishna...
BMCBI
2008
146views more  BMCBI 2008»
13 years 7 months ago
ProLoc-GO: Utilizing informative Gene Ontology terms for sequence-based prediction of protein subcellular localization
Background: Gene Ontology (GO) annotation, which describes the function of genes and gene products across species, has recently been used to predict protein subcellular and subnuc...
Wen-Lin Huang, Chun-Wei Tung, Shih-Wen Ho, Shiow-F...
BMCBI
2006
131views more  BMCBI 2006»
13 years 7 months ago
Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span
Background: The statistical modeling of biomedical corpora could yield integrated, coarse-to-fine views of biological phenomena that complement discoveries made from analysis of m...
David M. Blei, K. Franks, Michael I. Jordan, I. Sa...