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BMCBI
2008
134views more  BMCBI 2008»
13 years 9 months ago
Identification of transcription factor contexts in literature using machine learning approaches
Background: Availability of information about transcription factors (TFs) is crucial for genome biology, as TFs play a central role in the regulation of gene expression. While man...
Hui Yang, Goran Nenadic, John A. Keane
KDD
2004
ACM
117views Data Mining» more  KDD 2004»
14 years 9 months ago
Regularized multi--task learning
Past empirical work has shown that learning multiple related tasks from data simultaneously can be advantageous in terms of predictive performance relative to learning these tasks...
Theodoros Evgeniou, Massimiliano Pontil
KDD
2005
ACM
177views Data Mining» more  KDD 2005»
14 years 9 months ago
Query chains: learning to rank from implicit feedback
This paper presents a novel approach for using clickthrough data to learn ranked retrieval functions for web search results. We observe that users searching the web often perform ...
Filip Radlinski, Thorsten Joachims
BMCBI
2008
138views more  BMCBI 2008»
13 years 9 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...
BMCBI
2010
179views more  BMCBI 2010»
13 years 9 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...