Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
The construction of a text classifier usually involves (i) a phase of term selection, in which the most relevant terms for the classification task are identified, (ii) a phase ...
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
Background: The Gene Ontology Annotation (GOA) database http://www.ebi.ac.uk/GOA aims to provide high-quality supplementary GO annotation to proteins in the UniProt Knowledgebase....
Evelyn Camon, Daniel Barrell, Emily Dimmer, Vivian...
Kernels are two-placed functions that can be interpreted as inner products in some Hilbert space. It is this property which makes kernels predestinated to carry linear models of l...