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    BMCBI
    2010
    193views more  BMCBI 2010»
    Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
    13 years 8 months ago
    Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
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    Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
    Jakub Mieczkowski, Magdalena E. Tyburczy, Michal D...
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    BMCBI
    2010
    80views more  BMCBI 2010»
    Power and sample size estimation in microarray studies
    13 years 8 months ago
    Power and sample size estimation in microarray studies
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    Background: Before conducting a microarray experiment, one important issue that needs to be determined is the number of arrays required in order to have adequate power to identify...
    Wei-Jiun Lin, Huey-miin Hsueh, James J. Chen
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    BMCBI
    2008
    173views more  BMCBI 2008»
    Gene Vector Analysis (Geneva): A unified method to detect differentially-regulated gene sets and similar microarray experiments
    13 years 8 months ago
    Gene Vector Analysis (Geneva): A unified method to detect differentially-regulated gene sets and similar microarray experiments
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    Background: Microarray experiments measure changes in the expression of thousands of genes. The resulting lists of genes with changes in expression are then searched for biologica...
    Stephen W. Tanner, Pankaj Agarwal
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    BMCBI
    2008
    162views more  BMCBI 2008»
    Background correction using dinucleotide affinities improves the performance of GCRMA
    13 years 8 months ago
    Background correction using dinucleotide affinities improves the performance of GCRMA
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    Background: High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significan...
    Raad Z. Gharaibeh, Anthony Fodor, Cynthia Gibas
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    BMCBI
    2010
    156views more  BMCBI 2010»
    Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
    13 years 8 months ago
    Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
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    Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
    James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
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