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JCB
2002
160views more  JCB 2002»
13 years 9 months ago
Inference from Clustering with Application to Gene-Expression Microarrays
There are many algorithms to cluster sample data points based on nearness or a similarity measure. Often the implication is that points in different clusters come from different u...
Edward R. Dougherty, Junior Barrera, Marcel Brun, ...
BIOINFORMATICS
2002
146views more  BIOINFORMATICS 2002»
13 years 9 months ago
A duplication growth model of gene expression networks
Motivation: There has been considerable interest in developing computational techniques for inferring genetic regulatory networks from whole-genome expression profiles. When expre...
Ashish Bhan, David J. Galas, T. Gregory Dewey
BMCBI
2010
85views more  BMCBI 2010»
13 years 10 months ago
Robust test method for time-course microarray experiments
Background: In a time-course microarray experiment, the expression level for each gene is observed across a number of time-points in order to characterize the temporal trajectorie...
Insuk Sohn, Kouros Owzar, Stephen L. George, Sujon...
BMCBI
2004
115views more  BMCBI 2004»
13 years 9 months ago
Quantifying the relationship between co-expression, co-regulation and gene function
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte
BMCBI
2006
156views more  BMCBI 2006»
13 years 10 months ago
Bayesian models for pooling microarray studies with multiple sources of replications
Background: Biologists often conduct multiple but different cDNA microarray studies that all target the same biological system or pathway. Within each study, replicate slides with...
Erin M. Conlon, Joon J. Song, Jun S. Liu