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BMCBI
2008
146views more  BMCBI 2008»
13 years 8 months ago
Rank-based edge reconstruction for scale-free genetic regulatory networks
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
Guanrao Chen, Peter Larsen, Eyad Almasri, Yang Dai
PSB
2004
13 years 10 months ago
Modeling Cellular Processes with Variational Bayesian Cooperative Vector Quantizer
Gene expression of a cell is controlled by sophisticated cellular processes. The capability of inferring the states of these cellular processes would provide insight into the mech...
Xinghua Lu, Milos Hauskrecht, Roger S. Day
BMCBI
2004
108views more  BMCBI 2004»
13 years 8 months ago
Improving the scaling normalization for high-density oligonucleotide GeneChip expression microarrays
Background: Normalization is an important step for microarray data analysis to minimize biological and technical variations. Choosing a suitable approach can be critical. The defa...
Chao Lu
BMCBI
2010
214views more  BMCBI 2010»
13 years 8 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2005
121views more  BMCBI 2005»
13 years 8 months ago
Evaluation of gene importance in microarray data based upon probability of selection
Background: Microarray devices permit a genome-scale evaluation of gene function. This technology has catalyzed biomedical research and development in recent years. As many import...
Li M. Fu, Casey S. Fu-Liu