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BMCBI
2004
139views more  BMCBI 2004»
13 years 8 months ago
Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
Jeffrey P. Townsend
BMCBI
2006
103views more  BMCBI 2006»
13 years 8 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
BMCBI
2006
126views more  BMCBI 2006»
13 years 8 months ago
OpWise: Operons aid the identification of differentially expressed genes in bacterial microarray experiments
Background: Differentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no...
Morgan N. Price, Adam P. Arkin, Eric J. Alm
BMCBI
2006
153views more  BMCBI 2006»
13 years 8 months ago
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...
WCE
2007
13 years 9 months ago
Gene Selection for Tumor Classification Using Microarray Gene Expression Data
– In this paper we perform a t-test for significant gene expression analysis in different dimensions based on molecular profiles from microarray data, and compare several computa...
Krishna Yendrapalli, Ram B. Basnet, Srinivas Mukka...