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BMCBI
2010
233views more  BMCBI 2010»
13 years 8 months ago
Odefy -- From discrete to continuous models
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
Jan Krumsiek, Sebastian Pölsterl, Dominik M. ...
BMCBI
2006
111views more  BMCBI 2006»
13 years 8 months ago
Tools for integrated sequence-structure analysis with UCSF Chimera
Background: Comparing related structures and viewing the structures in the context of sequence alignments are important tasks in protein structure-function research. While many pr...
Elaine C. Meng, Eric F. Pettersen, Gregory S. Couc...
BMCBI
2005
130views more  BMCBI 2005»
13 years 8 months ago
Some statistical properties of regulatory DNA sequences, and their use in predicting regulatory regions in the Drosophila genome
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
Irina I. Abnizova, Rene te Boekhorst, Klaudia Walt...
BMCBI
2005
115views more  BMCBI 2005»
13 years 8 months ago
SUPERFICIAL - Surface mapping of proteins via structure-based peptide library design
Background: The determination of protein surfaces and the detection of binding sites are essential to our understanding of protein-protein interactions. Such binding sites can be ...
Andrean Goede, Ines S. Jaeger, Robert Preissner
BMCBI
2004
150views more  BMCBI 2004»
13 years 8 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty