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BMCBI
2010
122views more  BMCBI 2010»
13 years 7 months ago
Ovarian cancer classification based on dimensionality reduction for SELDI-TOF data
Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
Kai-Lin Tang, Tong-Hua Li, Wen-Wei Xiong, Kai Chen
BMCBI
2010
109views more  BMCBI 2010»
13 years 7 months ago
Pripper: prediction of caspase cleavage sites from whole proteomes
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
Mirva Piippo, Niina Lietzén, Olli Nevalaine...
BMCBI
2010
149views more  BMCBI 2010»
13 years 7 months ago
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...
Sigrid Rouam, Thierry Moreau, Philippe Broët
BMCBI
2010
156views more  BMCBI 2010»
13 years 7 months ago
Adaptive coarse-grained Monte Carlo simulation of reaction and diffusion dynamics in heterogeneous plasma membranes
Background: An adaptive coarse-grained (kinetic) Monte Carlo (ACGMC) simulation framework is applied to reaction and diffusion dynamics in inhomogeneous domains. The presented mod...
Stuart Collins, Michail Stamatakis, Dionisios G. V...
BMCBI
2010
138views more  BMCBI 2010»
13 years 7 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi
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