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AINA
2008
IEEE
14 years 3 months ago
Missing Value Estimation for Time Series Microarray Data Using Linear Dynamical Systems Modeling
The analysis of gene expression time series obtained from microarray experiments can be effectively exploited to understand a wide range of biological phenomena from the homeostat...
Connie Phong, Raul Singh
BILDMED
2007
107views Algorithms» more  BILDMED 2007»
13 years 10 months ago
Whole Body MRI Intensity Standardization
Abstract. A major problem of segmentation of magnetic resonance images is that intensities are not standardized like in computed tomography. This article deals with the correction ...
Florian Jäger, László G. Ny&uac...
BMCBI
2010
97views more  BMCBI 2010»
13 years 8 months ago
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...
BMCBI
2008
155views more  BMCBI 2008»
13 years 8 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 8 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...