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JCB
2007
144views more  JCB 2007»
13 years 10 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
PROMISE
2010
13 years 5 months ago
Defect cost flow model: a Bayesian network for predicting defect correction effort
Background. Software defect prediction has been one of the central topics of software engineering. Predicted defect counts have been used mainly to assess software quality and est...
Thomas Schulz, Lukasz Radlinski, Thomas Gorges, Wo...
BMCBI
2010
131views more  BMCBI 2010»
13 years 7 months ago
A two-step site and mRNA-level model for predicting microRNA targets
Background: Despite experiments showing that the number of microRNA (miRNA) target sites is critical for miRNA targeting, most existing methods focus on identifying individual miR...
Takaya Saito, Pål Sætrom
ICML
2004
IEEE
14 years 11 months ago
A graphical model for protein secondary structure prediction
In this paper, we present a graphical model for protein secondary structure prediction. This model extends segmental semi-Markov models (SSMM) to exploit multiple sequence alignme...
Wei Chu, Zoubin Ghahramani, David L. Wild
CEC
2009
IEEE
14 years 2 months ago
A parallel genetic algorithm for protein folding prediction using the 3D-HP Side Chain model
— This work presents a methodology for the application of a parallel genetic algorithm (PGA) to the problem of protein folding prediction, using the 3DHP-Side Chain model. This m...
César Manuel Vargas Benítez, Heitor ...