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BMCBI
2010
112views more  BMCBI 2010»
13 years 9 months ago
A parameter-adaptive dynamic programming approach for inferring cophylogenies
Background: Coevolutionary systems like hosts and their parasites are commonly used model systems for evolutionary studies. Inferring the coevolutionary history based on given phy...
Daniel Merkle, Martin Middendorf, Nicolas Wieseke
BMCBI
2008
135views more  BMCBI 2008»
13 years 9 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
BMCBI
2008
132views more  BMCBI 2008»
13 years 9 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
BMCBI
2008
160views more  BMCBI 2008»
13 years 9 months ago
Cross-species and cross-platform gene expression studies with the Bioconductor-compliant R package 'annotationTools'
Background: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cro...
Alexandre Kuhn, Ruth Luthi-Carter, Mauro Delorenzi
ALIFE
2006
13 years 9 months ago
Picture This: The State of the Art in Visualization for Complex Adaptive Systems
Visualization has an increasingly important role to play in scientific research. Moreover, visualization has a special role to play within artificial life as a result of the inform...
Seth Bullock, Tom Smith, Jon Bird