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RECOMB
2010
Springer
13 years 11 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
GECCO
2010
Springer
191views Optimization» more  GECCO 2010»
14 years 1 months ago
Initialization parameter sweep in ATHENA: optimizing neural networks for detecting gene-gene interactions in the presence of sma
Recent advances in genotyping technology have led to the generation of an enormous quantity of genetic data. Traditional methods of statistical analysis have proved insufficient i...
Emily Rose Holzinger, Carrie C. Buchanan, Scott M....
ICDE
2009
IEEE
290views Database» more  ICDE 2009»
14 years 10 months ago
GraphSig: A Scalable Approach to Mining Significant Subgraphs in Large Graph Databases
Graphs are being increasingly used to model a wide range of scientific data. Such widespread usage of graphs has generated considerable interest in mining patterns from graph datab...
Sayan Ranu, Ambuj K. Singh
INFOCOM
2009
IEEE
14 years 3 months ago
Delay-Optimal Opportunistic Scheduling and Approximations: The Log Rule
—This paper considers the design of opportunistic packet schedulers for users sharing a time-varying wireless channel from the performance and the robustness points of view. Firs...
Bilal Sadiq, Seung Jun Baek, Gustavo de Veciana
ISBRA
2010
Springer
13 years 7 months ago
A Consensus Tree Approach for Reconstructing Human Evolutionary History and Detecting Population Substructure
The random accumulation of variations in the human genome over time implicitly encodes a history of how human populations have arisen, dispersed, and intermixed since we emerged as...
Ming-Chi Tsai, Guy E. Blelloch, R. Ravi, Russell S...