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BMCBI
2010
97views more  BMCBI 2010»
13 years 8 months ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey
AB
2008
Springer
14 years 2 months ago
An Algorithm for Qualitative Simulation of Gene Regulatory Networks with Steep Sigmoidal Response Functions
A specific class of ODEs has been shown to be adequate to describe the essential features of the complex dynamics of Gene-Regulatory Networks (GRN). But, the effective exploitatio...
Liliana Ironi, Luigi Panzeri, Erik Plahte
EPEW
2008
Springer
13 years 10 months ago
A Ticking Clock: Performance Analysis of a Circadian Rhythm with Stochastic Process Algebra
We apply performance analysis techniques to a biological modelling problem, that of capturing and reproducing the Circadian rhythm. A Circadian rhythm provides cells with a clock b...
Jeremy T. Bradley
BMCBI
2010
164views more  BMCBI 2010»
13 years 8 months ago
Gene regulatory networks modelling using a dynamic evolutionary hybrid
Background: Inference of gene regulatory networks is a key goal in the quest for understanding fundamental cellular processes and revealing underlying relations among genes. With ...
Ioannis A. Maraziotis, Andrei Dragomir, Dimitris T...
RECOMB
2003
Springer
14 years 9 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...