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160
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CORR
2012
Springer
210views Education» more  CORR 2012»
13 years 10 months ago
Fast MCMC sampling for Markov jump processes and continuous time Bayesian networks
Markov jump processes and continuous time Bayesian networks are important classes of continuous time dynamical systems. In this paper, we tackle the problem of inferring unobserve...
Vinayak Rao, Yee Whye Teh
132
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BMCBI
2010
152views more  BMCBI 2010»
15 years 2 months ago
Comparative study of discretization methods of microarray data for inferring transcriptional regulatory networks
Background: Microarray data discretization is a basic preprocess for many algorithms of gene regulatory network inference. Some common discretization methods in informatics are us...
Yong Li, Lili Liu, Xi Bai, Hua Cai, Wei Ji, Dianji...
121
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SAC
2008
ACM
15 years 2 months ago
Bayesian inference for a discretely observed stochastic kinetic model
The ability to infer parameters of gene regulatory networks is emerging as a key problem in systems biology. The biochemical data are intrinsically stochastic and tend to be observ...
Richard J. Boys, Darren J. Wilkinson, Thomas B. L....
126
Voted
CMSB
2009
Springer
15 years 9 months ago
Probabilistic Approximations of Signaling Pathway Dynamics
Systems of ordinary differential equations (ODEs) are often used to model the dynamics of complex biological pathways. We construct a discrete state model as a probabilistic appro...
Bing Liu, P. S. Thiagarajan, David Hsu
BMCBI
2005
178views more  BMCBI 2005»
15 years 2 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...