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CIBCB
2007
IEEE
14 years 1 months ago
Modeling protein-DNA binding time in Stochastic Discrete Event Simulation of Biological Processes
Abstract— This paper presents a parametric model to estimate the DNA-protein binding time using the DNA and protein structures and details of the binding site. To understand the ...
Preetam Ghosh, Samik Ghosh, Kalyan Basu, Sajal K. ...
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
14 years 12 days ago
iSimBioSys: An "In Silico" Discrete Event Simulation Framework for Modeling Biological Systems
The genome projects have provided comprehensive information about the basic building blocks of life. The next challenge is to understand how biological functions emerge from compl...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
CMSB
2009
Springer
14 years 1 months ago
Approximation of Event Probabilities in Noisy Cellular Processes
Molecular noise, which arises from the randomness of the discrete events in the cell, significantly influences fundamental biological processes. Discrete-state continuous-time st...
Frédéric Didier, Thomas A. Henzinger...
ANSS
2006
IEEE
14 years 26 days ago
iSimBioSys: A Discrete Event Simulation Platform for 'in silico' study of biological systems
With the availability of huge databases cataloguing the various molecular “parts” of complex biological systems, researchers from multiple disciplines have focused on developi...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
FPGA
2004
ACM
174views FPGA» more  FPGA 2004»
14 years 5 days ago
A compiled accelerator for biological cell signaling simulations
The simulation of large systems of biochemical reactions is a key part of research into molecular signaling and information processing in biological cells. However, it can be impr...
John F. Keane, Christopher Bradley, Carl Ebeling