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BMCBI
2010
105views more  BMCBI 2010»
13 years 8 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2010
156views more  BMCBI 2010»
13 years 8 months ago
Extended morphological processing: a practical method for automatic spot detection of biological markers from microscopic images
Background: A reliable extraction technique for resolving multiple spots in light or electron microscopic images is essential in investigations of the spatial distribution and dyn...
Yoshitaka Kimori, Norio Baba, Nobuhiro Morone
SIGIR
2011
ACM
12 years 11 months ago
Mining tags using social endorsement networks
Entities on social systems, such as users on Twitter, and images on Flickr, are at the core of many interesting applications: they can be ranked in search results, recommended to ...
Theodoros Lappas, Kunal Punera, Tamás Sarlo...
ICDE
2006
IEEE
149views Database» more  ICDE 2006»
14 years 10 months ago
How to Determine a Good Multi-Programming Level for External Scheduling
Scheduling/prioritization of DBMS transactions is important for many applications that rely on database backends. A convenient way to achieve scheduling is to limit the number of ...
Bianca Schroeder, Mor Harchol-Balter, Arun Iyengar...
SIGMOD
2008
ACM
191views Database» more  SIGMOD 2008»
14 years 8 months ago
Efficient aggregation for graph summarization
Graphs are widely used to model real world objects and their relationships, and large graph datasets are common in many application domains. To understand the underlying character...
Yuanyuan Tian, Richard A. Hankins, Jignesh M. Pate...