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BMCBI
2010
145views more  BMCBI 2010»
13 years 7 months ago
Clustering metagenomic sequences with interpolated Markov models
Background: Sequencing of environmental DNA (often called metagenomics) has shown tremendous potential to uncover the vast number of unknown microbes that cannot be cultured and s...
David R. Kelley, Steven L. Salzberg
SOCRATES
2008
125views Education» more  SOCRATES 2008»
13 years 9 months ago
Collaborative Knowledge Construction in Online Vocational Teacher Education
The purpose of this paper is to build a picture of knowledge construction models in online education. The study describes the knowledge construction process of a group of vocation...
Raimo Mäkelä, Marjatta Myllylä, Han...
GECCO
2008
Springer
177views Optimization» more  GECCO 2008»
13 years 8 months ago
Reduced computation for evolutionary optimization in noisy environment
Evolutionary Algorithms’ (EAs’) application to real world optimization problems often involves expensive fitness function evaluation. Naturally this has a crippling effect on ...
Maumita Bhattacharya
WSC
1998
13 years 9 months ago
Integrating Neural Networks with Special Purpose Simulation
Traditional methods of dealing with variability in simulation input data are mainly stochastic. This is most often the best method to use if the factors affecting the variation or...
Dany Hajjar, Simaan M. AbouRizk, Kevin Mather
BMCBI
2006
118views more  BMCBI 2006»
13 years 7 months ago
Predicting the effect of missense mutations on protein function: analysis with Bayesian networks
Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
Chris J. Needham, James R. Bradford, Andrew J. Bul...