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» Modelling Developmental Regulatory Networks
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IJKDB
2010
141views more  IJKDB 2010»
13 years 5 months ago
Mining Frequent Boolean Expressions: Application to Gene Expression and Regulatory Modeling
Regulatory network analysis and other bioinformatics tasks require the ability to induce and represent arbitrary boolean expressions from data sources. We introduce a novel framew...
Mohammed Javeed Zaki, Naren Ramakrishnan, Lizhuang...
CEC
2003
IEEE
13 years 11 months ago
Dynamics of gene expression in an artificial genome
Abstract- Complex systems techniques provide a powerful tool to study the emergent properties of networks of interacting genes. In this study we extract models of genetic regulator...
Kai Willadsen, Janet Wiles
BMCBI
2010
129views more  BMCBI 2010»
13 years 8 months ago
Uncovering packaging features of co-regulated modules based on human protein interaction and transcriptional regulatory networks
Background: Network co-regulated modules are believed to have the functionality of packaging multiple biological entities, and can thus be assumed to coordinate many biological fu...
Lina Chen, Hong Wang, Liangcai Zhang, Wan Li, Qian...
BMCBI
2004
146views more  BMCBI 2004»
13 years 7 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
JMLR
2012
11 years 10 months ago
Bayesian regularization of non-homogeneous dynamic Bayesian networks by globally coupling interaction parameters
To relax the homogeneity assumption of classical dynamic Bayesian networks (DBNs), various recent studies have combined DBNs with multiple changepoint processes. The underlying as...
Marco Grzegorczyk, Dirk Husmeier