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BMCBI
2010
136views more  BMCBI 2010»
13 years 7 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2008
130views more  BMCBI 2008»
13 years 7 months ago
An enhanced partial order curve comparison algorithm and its application to analyzing protein folding trajectories
Background: Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produc...
Hong Sun, Hakan Ferhatosmanoglu, Motonori Ota, Yus...
JUCS
2008
112views more  JUCS 2008»
13 years 7 months ago
Knowledge Processing in Intelligent Systems
Abstract: Intelligence and Knowledge play more and more important roles in building complex intelligent systems, for instance, intrusion detection systems, and operational analysis...
Longbing Cao, Ngoc Thanh Nguyen
BMCBI
2004
114views more  BMCBI 2004»
13 years 7 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
PVLDB
2010
128views more  PVLDB 2010»
13 years 6 months ago
Update Rewriting and Integrity Constraint Maintenance in a Schema Evolution Support System: PRISM++
Supporting legacy applications when the database schema evolves represents a long-standing challenge of practical and theoretical importance. Recent work has produced algorithms a...
Carlo Curino, Hyun Jin Moon, Alin Deutsch, Carlo Z...