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» Modelling Gene Regulatory Networks
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GRC
2005
IEEE
14 years 3 months ago
A linear control model for gene intervention in a genetic regulatory network
In this paper, we propose a linear control model for gene intervention in a genetic regulatory network. At each time step, finite controls are allowed to drive the network states...
Shuqin Zhang, Michael K. Ng, Wai-Ki Ching, Tatsuya...
IDEAL
2004
Springer
14 years 3 months ago
Building Genetic Networks for Gene Expression Patterns
Building genetic regulatory networks from time series data of gene expression patterns is an important topic in bioinformatics. Probabilistic Boolean networks (PBNs) have been deve...
Wai-Ki Ching, Eric S. Fung, Michael K. Ng
TIT
2010
97views Education» more  TIT 2010»
13 years 4 months ago
Periodic orbits and equilibria in glass models for gene regulatory networks
Abstract--Glass models are frequently used to model gene regulatory networks. A distinct feature of the Glass model is that its dynamics can be formalized as paths through multi-di...
Igor Zinovik, Yury Chebiryak, Daniel Kroening
CMA
2010
87views more  CMA 2010»
13 years 7 months ago
A modified uniformization method for the solution of the chemical master equation
The chemical master equation is considered an accurate description of general chemical systems, and especially so for modeling cell cycle and gene regulatory networks. This paper ...
Jingwei Zhang, Layne T. Watson, Yang Cao
ISBRA
2009
Springer
14 years 4 months ago
Using Gene Expression Modeling to Determine Biological Relevance of Putative Regulatory Networks
Identifying gene regulatory networks from high-throughput gene expression data is one of the most important goals of bioinformatics, but it remains difficult to define what makes a...
Peter Larsen, Yang Dai