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» Models and Methods in Comparative Genomics
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BMCBI
2010
133views more  BMCBI 2010»
13 years 10 months ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...
GECCO
2000
Springer
123views Optimization» more  GECCO 2000»
14 years 1 months ago
Genomic computing: explanatory modelling for functional genomics
Many newly discovered genes are of unknown function. DNA microarrays are a method for determining the expression levels of all genes in an organism for which a complete genome seq...
Richard J. Gilbert, Jem J. Rowland, Douglas B. Kel...
BMCBI
2010
150views more  BMCBI 2010»
13 years 9 months ago
DeltaProt: a software toolbox for comparative genomics
Background: Statistical bioinformatics is the study of biological data sets obtained by new micro-technologies by means of proper statistical methods. For a better understanding o...
Steinar Thorvaldsen, Tor Flå, Nils Willassen
BMCBI
2006
156views more  BMCBI 2006»
13 years 9 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
HICSS
2003
IEEE
166views Biometrics» more  HICSS 2003»
14 years 3 months ago
Comparative Genome Annotation for Mapping, Prediction and Discovery of Genes
We have used comparative genome analyses to produce annotated maps for large genomic loci. The first example is a locus on mouse chromosome 9 that is syntenic to human chromosome ...
Claudia Kappen, J. Michael Salbaum