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BMCBI
2010
112views more  BMCBI 2010»
13 years 10 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner
BMCBI
2010
161views more  BMCBI 2010»
13 years 10 months ago
BPDA - A Bayesian peptide detection algorithm for mass spectrometry
Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
Youting Sun, Jianqiu Zhang, Ulisses Braga-Neto, Ed...
BMCBI
2004
153views more  BMCBI 2004»
13 years 9 months ago
Computational protein biomarker prediction: a case study for prostate cancer
Background: Recent technological advances in mass spectrometry pose challenges in computational mathematics and statistics to process the mass spectral data into predictive models...
Michael Wagner, Dayanand N. Naik, Alex Pothen, Sri...
JCSC
2002
129views more  JCSC 2002»
13 years 9 months ago
Leakage Current Reduction in VLSI Systems
There is a growing need to analyze and optimize the stand-by component of power in digital circuits designed for portable and battery-powered applications. Since these circuits re...
David Blaauw, Steven M. Martin, Trevor N. Mudge, K...
NECO
2007
129views more  NECO 2007»
13 years 9 months ago
Variational Bayes Solution of Linear Neural Networks and Its Generalization Performance
It is well-known that, in unidentifiable models, the Bayes estimation provides much better generalization performance than the maximum likelihood (ML) estimation. However, its ac...
Shinichi Nakajima, Sumio Watanabe