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BMCBI
2011
13 years 4 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
BMCBI
2008
102views more  BMCBI 2008»
13 years 10 months ago
Monitoring the evolutionary aspect of the Gene Ontology to enhance predictability and usability
Background: Much effort is currently made to develop the Gene Ontology (GO). Due to the dynamic nature of information it addresses, GO undergoes constant updates whose results are...
Jong C. Park, Tak-eun Kim, Jinah Park
BMCBI
2010
277views more  BMCBI 2010»
13 years 10 months ago
PCA2GO: a new multivariate statistics based method to identify highly expressed GO-Terms
Background: Several tools have been developed to explore and search Gene Ontology (GO) databases allowing efficient GO enrichment analysis and GO tree visualization. Nevertheless,...
Marc Bruckskotten, Mario Looso, Franz Cemic, Anne ...
ICANN
2010
Springer
13 years 10 months ago
Multi-Dimensional Deep Memory Atari-Go Players for Parameter Exploring Policy Gradients
Abstract. Developing superior artificial board-game players is a widelystudied area of Artificial Intelligence. Among the most challenging games is the Asian game of Go, which, des...
Mandy Grüttner, Frank Sehnke, Tom Schaul, J&u...
COMPLEX
2009
Springer
14 years 4 months ago
Designing Capital-Intensive Systems with Architectural and Operational Flexibility Using a Screening Model
: Development of capital intensive systems, such as offshore oil platforms or other industrial infrastructure, generally requires a significant amount of capital investment under v...
Jijun Lin, Olivier de Weck, Richard de Neufville, ...