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BMCBI
2010
196views more  BMCBI 2010»
15 years 1 months ago
Content-based microarray search using differential expression profiles
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
Jesse M. Engreitz, Alexander A. Morgan, Joel Dudle...
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BMCBI
2010
119views more  BMCBI 2010»
15 years 1 months ago
The INTERPRET Decision-Support System version 3.0 for evaluation of Magnetic Resonance Spectroscopy data from human brain tumour
Background: Proton Magnetic Resonance (MR) Spectroscopy (MRS) is a widely available technique for those clinical centres equipped with MR scanners. Unlike the rest of MR-based tec...
Alexander Pérez-Ruiz, Margarida Julià...
BMCBI
2010
161views more  BMCBI 2010»
15 years 1 months ago
Addressing the Challenge of Defining Valid Proteomic Biomarkers and Classifiers
Background: The purpose of this manuscript is to provide, based on an extensive analysis of a proteomic data set, suggestions for proper statistical analysis for the discovery of ...
Mohammed Dakna, Keith Harris, Alexandros Kalousis,...
BMCBI
2010
218views more  BMCBI 2010»
15 years 1 months ago
A hybrid blob-slice model for accurate and efficient detection of fluorescence labeled nuclei in 3D
Background: To exploit the flood of data from advances in high throughput imaging of optically sectioned nuclei, image analysis methods need to correctly detect thousands of nucle...
Anthony Santella, Zhuo Du, Sonja Nowotschin, Anna-...
BMCBI
2010
154views more  BMCBI 2010»
15 years 1 months ago
Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation
Background: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gen...
Andreas Kowarsch, Florian Blöchl, Sebastian B...
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