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BMCBI
2011
13 years 1 months ago
Efficient alignment of pyrosequencing reads for re-sequencing applications
Background: Over the past few years, new massively parallel DNA sequencing technologies have emerged. These platforms generate massive amounts of data per run, greatly reducing th...
Francisco Fernandes, Paulo G. S. da Fonseca, Lu&ia...
BMCBI
2011
13 years 1 months ago
Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Datase
Background: Diabetes like many diseases and biological processes is not mono-causal. On the one hand multifactorial studies with complex experimental design are required for its c...
Chris Bauer, Frank Kleinjung, Celia J. Smith, Mark...
BMCBI
2011
13 years 1 months ago
To aggregate or not to aggregate high-dimensional classifiers
Background: High-throughput functional genomics technologies generate large amount of data with hundreds or thousands of measurements per sample. The number of sample is usually m...
Cheng-Jian Xu, Huub C. J. Hoefsloot, Age K. Smilde
BMCBI
2011
13 years 1 months ago
PRIN, a predicted rice interactome network
Background: Protein-protein interactions play a fundamental role in elucidating the molecular mechanisms of biomolecular function, signal transductions and metabolic pathways of l...
Haibin Gu, Pengcheng Zhu, Yinming Jiao, Yijun Meng...
BMCBI
2011
13 years 1 months ago
Assessing the functional coherence of modules found in multiple-evidence networks from Arabidopsis
Background: Combining multiple evidence-types from different information sources has the potential to reveal new relationships in biological systems. The integrated information ca...
Artem Lysenko, Michael Defoin-Platel, Keywan Hassa...
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