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BMCBI
2010
100views more  BMCBI 2010»
13 years 8 months ago
MapMi: automated mapping of microRNA loci
Background: A large effort to discover microRNAs (miRNAs) has been under way. Currently miRBase is their primary repository, providing annotations of primary sequences, precursors...
José Afonso Guerra-Assunção, ...
BMCBI
2010
182views more  BMCBI 2010»
13 years 8 months ago
L2-norm multiple kernel learning and its application to biomedical data fusion
Background: This paper introduces the notion of optimizing different norms in the dual problem of support vector machines with multiple kernels. The selection of norms yields diff...
Shi Yu, Tillmann Falck, Anneleen Daemen, Lé...
BMCBI
2010
127views more  BMCBI 2010»
13 years 8 months ago
SplicerAV: a tool for mining microarray expression data for changes in RNA processing
Background: Over the past two decades more than fifty thousand unique clinical and biological samples have been assayed using the Affymetrix HG-U133 and HG-U95 GeneChip microarray...
Timothy J. Robinson, Michaela A. Dinan, Mark Dewhi...
BMCBI
2010
165views more  BMCBI 2010»
13 years 8 months ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...
BMCBI
2010
99views more  BMCBI 2010»
13 years 8 months ago
Prediction of novel precursor miRNAs using a context-sensitive hidden Markov model (CSHMM)
Background: It has been apparent in the last few years that small non coding RNAs (ncRNA) play a very significant role in biological regulation. Among these microRNAs (miRNAs), 22...
Sumeet Agarwal, Candida Vaz, Alok Bhattacharya, As...
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